Owner contribution
Here is my Tamrac CyberPak 8 in "heavy mode".

The CyberPack 8 combines a laptop, digital or film SLR equipment and accessories in one convenient, easy-to-carry backpack. The main compartment accommodates multiple camera bodies, a long telephoto lens up to 13½" attached to an SLR, an array of additional lenses, and strobes. This larger sized pack also accommodates large laptops such as Apple's 17" PowerBook G4 and others up to 11" X 2" X 15½". Windowpane-Mesh™ accessory pockets visibly store AC adapters, cables and other accessories. A professional tripod can be securely carried using Tamrac's QuickClip™ tripod attachment system. A front accessory pocket organizes CDs, a PDA, business cards, pens and cables and features Tamrac's U.S. patented Memory & Battery Management System™ that uses red flags to identify which memory cards and batteries are available for use. This pack is completely padded with thick, closed-cell foam and has a foam-padded plastic platform in the bottom to provide shock protection. A thickly padded shoulder harness, padded hip belt, and sternum strap ease the burden of carrying this well-equipped pack. Accepts Tamrac's Modular Accessory System™ (M.A.S.™) and Strap Accessory System™ (S.A.S.™) products to allow for complete customization.
multiple camera bodies, a long telephoto lens up to 13½
Here is my Tamrac CyberPak 8 in "heavy mode".
Not shown: outer flap which holds CF and SD along with my strap, pens, business cards etc..also not shown is the laptop sleeve on the underside.
I've got a Tamrac Cyber 8 that I'm selling. Too big for me and might be what you're looking for. Never been out in the light of day or on the road. I bought it new from B&H Photo but never used it outdoors. I use to use it to store my gear before buying a Pelican case. It also has a laptop section that holds a 17" laptop. Holds everything in my sig except for the 300 f/2.8. It is deep enough to stack lenses with padding in between. The empty spots are for a metz flash, Canon EF 24-70mm f/2.8L USM and a Canon EOS 1D mk II body